Coding
Part:BBa_K3657024:Design
Designed by: Julia Langer Group: iGEM20_Heidelberg (2020-10-21)
SoxS Trancription Activator
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The aminoacid sequence was obtained from the Uniprot database (P0A9E2). The nucletide sequence was then generated and codon optimised for E. coli.
Source
Escherichia coli
References
Wu J, Weiss B. Two-stage induction of the soxRS (superoxide response) regulon of Escherichia coli. J Bacteriol. 1992;174(12):3915-3920.
Dong C, Fontana J, Patel A, Carothers JM, Zalatan JG. Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria [published correction appears in Nat Commun. 2018 Oct 15;9(1):4318]. Nat Commun. 2018;9(1):2489.
This part on Uniprot: https://www.uniprot.org/uniprot/P0A9E2